Journal: Scientific Reports

Article Title: Seroprevalence of Toxoplasma gondii and Borrelia burgdorferi infections in patients with multiple sclerosis in Poland

doi: 10.1038/s41598-024-61714-y

Figure Lengend Snippet: Stratification by age in cases and controls for IgM and IgG seropositivity to T. gondii and B. burgdorferi .

Article Snippet: For confirmation of positive or doubtful results of Borrelia ELISA test, Western Blot test (Anti- Borrelia IgM and IgG Line Immunoassay, DRG Instruments GmbH, Marburg, Germany) was performed according to the recommendations of The Polish Society of Epidemiology and Infectious Disease and European guidelines .

Techniques: Enzyme-linked Immunosorbent Assay

Journal: Diagnostics

Article Title: Detection of Myositis Autoantibodies by Multi-Analytic Immunoassays in a Large Multicenter Cohort of Patients with Definite Idiopathic Inflammatory Myopathies

doi: 10.3390/diagnostics13193080

Figure Lengend Snippet: Analytical characteristics of current commercial multi-analytic immunoassays for the detection of myositis autoantibodies.

Article Snippet: MSAs and MAAs were determined by commercial line immunoassay (LIA, Euroline® Myositis profile 3, 16 Ags, Euroimmun, Lübeck, Germany; Mi-2α, Mi-2β, TIF1γ, MDA5, NXP2, SAE1, Ku, PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro52).

Techniques: Immunopeptidomics, Recombinant, Affinity Purification

Journal: Diagnostics

Article Title: Detection of Myositis Autoantibodies by Multi-Analytic Immunoassays in a Large Multicenter Cohort of Patients with Definite Idiopathic Inflammatory Myopathies

doi: 10.3390/diagnostics13193080

Figure Lengend Snippet: Frequency of myositis-specific antibodies (MSAs) and myositis-associated antibodies (MAAs) (number, percentual values) in 411 patients affected with definite idiopathic inflammatory myopathies (IIMs), detected by line immunoassay (LIA). Anti-HMGCR was determined in 157/411 IIMs by enzyme-linked immunosorbent assay (ELISA).

Article Snippet: MSAs and MAAs were determined by commercial line immunoassay (LIA, Euroline® Myositis profile 3, 16 Ags, Euroimmun, Lübeck, Germany; Mi-2α, Mi-2β, TIF1γ, MDA5, NXP2, SAE1, Ku, PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro52).

Techniques: Enzyme-linked Immunosorbent Assay

Journal: Diagnostics

Article Title: Detection of Myositis Autoantibodies by Multi-Analytic Immunoassays in a Large Multicenter Cohort of Patients with Definite Idiopathic Inflammatory Myopathies

doi: 10.3390/diagnostics13193080

Figure Lengend Snippet: Diagnostic accuracy of myositis-specific antibodies (MSAs) detected by line immunoassay (LIA) in patients with idiopathic inflammatory myopathies (IIMs) and controls.

Article Snippet: MSAs and MAAs were determined by commercial line immunoassay (LIA, Euroline® Myositis profile 3, 16 Ags, Euroimmun, Lübeck, Germany; Mi-2α, Mi-2β, TIF1γ, MDA5, NXP2, SAE1, Ku, PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro52).

Techniques: Diagnostic Assay

Journal: Diagnostics

Article Title: Detection of Myositis Autoantibodies by Multi-Analytic Immunoassays in a Large Multicenter Cohort of Patients with Definite Idiopathic Inflammatory Myopathies

doi: 10.3390/diagnostics13193080

Figure Lengend Snippet: Individual myositis-specific antibody (MSA) positivity detected in 89 IIM sera by particle-based multi-analyte technology (PMAT): concordance/discordance with line immunoassay (LIA) and HMGCR ELISA results are depicted. Filled dots are concordant results between the methods, and open dots are discordant results between the methods.

Article Snippet: MSAs and MAAs were determined by commercial line immunoassay (LIA, Euroline® Myositis profile 3, 16 Ags, Euroimmun, Lübeck, Germany; Mi-2α, Mi-2β, TIF1γ, MDA5, NXP2, SAE1, Ku, PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro52).

Techniques: Enzyme-linked Immunosorbent Assay

Journal: Diagnostics

Article Title: Detection of Myositis Autoantibodies by Multi-Analytic Immunoassays in a Large Multicenter Cohort of Patients with Definite Idiopathic Inflammatory Myopathies

doi: 10.3390/diagnostics13193080

Figure Lengend Snippet: A 1:1 comparison of multiple positive results between the line immunoassay (LIA) and the particle-based multi-analyte technology (PMAT) in IIM patients’ sera ( n = 11).

Article Snippet: MSAs and MAAs were determined by commercial line immunoassay (LIA, Euroline® Myositis profile 3, 16 Ags, Euroimmun, Lübeck, Germany; Mi-2α, Mi-2β, TIF1γ, MDA5, NXP2, SAE1, Ku, PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro52).

Techniques: Comparison, Biomarker Discovery

Journal: Diagnostics

Article Title: Detection of Myositis Autoantibodies by Multi-Analytic Immunoassays in a Large Multicenter Cohort of Patients with Definite Idiopathic Inflammatory Myopathies

doi: 10.3390/diagnostics13193080

Figure Lengend Snippet: Clinical associations of myositis autoantibodies detected by line immunoassay (LIA) with IIM subgroups. The frequency of individual antibodies in the different IIM subsets is depicted. ** p < 0.001.

Article Snippet: MSAs and MAAs were determined by commercial line immunoassay (LIA, Euroline® Myositis profile 3, 16 Ags, Euroimmun, Lübeck, Germany; Mi-2α, Mi-2β, TIF1γ, MDA5, NXP2, SAE1, Ku, PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, Ro52).

Techniques: